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The SLC22 organic cation transporters are suggested to be lower affinity ( K m 1.5 mM) choline transporters, but are also selectively expressed, and not thought to be responsible for basal-level choline uptake (21)
Compounds with minimal evidence being marketed as breakthroughs
This process limits the uptake of DOX and promotes the emergence of drug resistance 44
Why oral matters One major practical advantage of products like Motus is that they are oral
The doses range from 2 to 6 IU each day
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