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doi: 10.1016/j.physbeh.2010.02.029 18 AlhadeffALRupprechtLEHayesMR

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On the other hand, ILC3 is upregulated in psoriatic skin, producing mediators like IL-17 and IL-22, which contribute to mucosal immunity and tissue repair (91)

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When Phase 1 activity exceeds Phase 2 capacity, reactive intermediate metabolites may accumulate faster than they can be neutralized

A study synthesized a gold nanoparticle-based dual-targeting platform co-loaded with HER2-siRNA and doxorubicin, which exhibited potent antiproliferative and ferroptosis-inducing effects in a HER2-positive breast cancer model, and achieved tumor-specific activation via a pH-responsive release system (151)