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Oxidation of Pro generates NADP/NADPH cycling or redox balance (Kishor et al., 2005) that in turn may regulate the reduction of GSSG to GSH via GSH reductase (Anjum et al., 2010, 2012a

Cherta-Murillo A, Lett AM, Frampton J, Chambers ES, Finnigan TJA, Frost GS

Even the mid-range doses (4 mg and 8 mg) promoted significant reductions of 17.1% and 22.8%

The GSH:GSSG (reduced:oxidized) couple is the principal buffer of intracellular redox state

While a promising approach, future work to address product stability and efficacy in larger eyes is needed for further development

Rhodiola, for example, is a plant that contains polyphenols, glycosides, organic acids, essential oils, alcohols, proteins, sugars, and fats