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The FDA's decision was based on two late-stage trials in which Lipfendra cut LDL levels by 56% to 59% compared to a placebo

Orta et al

Tirzepatide has extensive Phase 3 and post-marketing safety data through Mounjaro and Zepbound

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It is based on the active sequence of epithalamin a polypeptide extract from the pineal gland and has been studied extensively for telomerase activation, antioxidant effects, and biological aging modulation in preclinical and Russian clinical research spanning more than three decades