"Dosing" refers exclusively to amounts used in mouse experiments and is not applicable to humans
Sci Transl Med 7: 289ra86, 2015
The therapy was applied intraperitoneally 30 min after surgery and once a day until one day before sacrificing on 1st, 4th, 7th, 10th and 14th day after transection (10)
Taylor & Francis, Washington, pp pp
For patients with type 2 diabetes and biopsy-proven NASH with fibrosis, pioglitazone may be considered under specialist supervision, as its use for liver disease is outside its licensed indication (type 2 diabetes) and requires careful assessment of potential risks and contraindications
Therefore, researchers can observe how signaling responses change when peptides work within the same model and when study variables remain controlled