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Additionally, CHAC1 enhances the sensitivity of prostate cancer cells to the chemotherapy drug docetaxel (DTX)

LCMS/MS and pathway analysis LCMS/MS samples were prepared according to a Filter-aided Sample Preparation (FASP) method 69

Phase II Metabolism: Phase II metabolism typically follows Phase I metabolism, using the transformed metabolites or the parent compound as substrates for conjugation reactions

Titration of a recombinant N-terminal domain of p53 (aa1-312) to a solution containing the 1H, 15N-labelled FOXO4 Forkhead (FH) Domain (aa486-206) induced a progressive chemical shift perturbation (CSPs) of 1H, 15N HSQC cross peaks, indicating specific binding of p53 to FOXO4 (Fig

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Schwab et al., 2014) Eradication is difficult for many of these pathogens due to the increased viscoelasticity of the mucus, antibiotic resistance of the bacteria, and antibiotic tolerance from biofilm formation of bacteria within the mucus (Singh et al., 2000