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Pharmacological inhibitors and siRNA-mediated knockdown of p38 completely suppressed IL-10 production in primary cultured microglia [63]

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These results suggest that the interaction between G3BP and ASPLs UBX+ region enhances G3BP condensation, alters the material properties of the SG condensate, and stabilizes the interaction of G3BP with other SG constituents, ultimately reducing the exchange rate between SG-localized G3BP with cytosolic G3BP and promoting SG formation

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