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Astrocytic metabolic and inflammatory changes as a function of age

Nat Commun 15 , 6152 (2024)

Combining glutamine-targeted treatments with oncogene inhibitors may create synthetic lethality

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The process is dynamic, and involves also the thiolate groups of proteins such as serum albumin and haemoglobin and appears as the main mechanism for the distribution of thiol-binding metals from the absorption site throughout the body and towards the active sites where the toxic action is developed at the molecular level

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