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What the Current Clinical Evidence Shows Phase 2 trial data published in the NEJM in 2023 show gastrointestinal events including nausea were the most common side effects, were transient and self-limiting in most participants, and were more frequent at higher doses

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The combination creates a metabolic state that is extremely favorable for rapid, sustained fat loss

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Kaler SG, Patrinos ME, Lambert GH, et al