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As a retrospective analysis of electronic health records, it is susceptible to selection and ascertainment bias, and cardiovascular conditions and outcomes were identified primarily using ICD diagnostic codes, which may not always reflect specialist-confirmed diagnoses

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administration of d-allulose (1 and 3 g kg 1 ) at the LP onset 7:30 attenuated LP hyperphagia without altering DP food intake, thereby improving diurnal feeding rhythm in HFD-fed mice (Figs