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As ongoing reviews and published results expand, researchers can expect more refined dosage and stability guidelines to emerge, allowing even greater precision when preparing the reconstituted solution for future experiments

Because the oxidationreduction of Fe 2+ to Fe 3+ requires electron transfer, iron is involved in the electron migration between substrates ( 2+ or Fe 3+ ions and hydrogen peroxide (H 2 O 2 ) to produce highly reactive hydroxyl radicals (Fenton, 1894), which increased ROS level in cells and triggered the peroxidation of polyunsaturated fatty acids (PUFAs) or saturated fatty acids in membrane lipids (Lachaier et al., 2014)

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A Glutathione normally exists in the reduced form (GSH) in the body but is converted to the oxidized form (GSSG) by stimuli such as oxidative stress