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One of the strongest prosurvival pathways implicated in the development of NBL and linked to a bad prognosis is phosphatidylinositol 3kinase (PI3K), protein kinase B (Akt), and mammalian target of rapamycin (mTOR) pathway (Sui et al., 2014)

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doi: 10.1042/bst0300093 11 DirksenAPiitulainenEParrDGDengCWenckerMShakerSBet al