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There are specific scenarios where combining these two forms of B12 might be considered, as part of a tailored treatment plan: Reducing Injection Frequency: For some individuals who require lifelong B12 due to malabsorption but dislike frequent injections, a doctor might explore if high-dose oral supplements can help maintain adequate levels between less frequent injections

For severe trauma, major surgeries, or time-sensitive recovery needs, starting with BPC/TB-15 may be most appropriate

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Medicare: Medicare pays for CPT code 96372 in office settings under the Physician Fee Schedule