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It also has some anti-neoplastic (anti-cancer) action since it stimulates the production of interferon, tumor necrosis factor and seems to speed regeneration of normal cells

Dysfunction of nAChRs (antagonism or desensitization) is crucial to abolish nicotine dependence and the maintenance of an appropriate level of extracellular dopamine eliminates nicotine withdrawal syndromes

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Recognising this distinction is important when assessing changes in your skin