Results showed a significant reduction in Body Mass Index (BMI) over 24 months, with mean differences of 0.36, 1.08, 1.18, and 1.42 at 3, 6, 12, and 24 months, respectively, with 95% CI, and low heterogeneity ( I = 0.0%)
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Many patients do have an initial response
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However, you should speak to a healthcare professional if: Cold intolerance is severe or worsening You feel dizzy, faint, or extremely fatigued Symptoms persist despite eating adequately You have a history of thyroid problems or anaemia These situations may require a review to rule out other causes
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