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In the 1990s, researchers discovered that Gila monster saliva contains a peptide called exendin-4, which acts like GLP-1 but resists enzymatic breakdown

10.1016/j.psyneuen.2019.02.006 71 VallofD.KalafateliA

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These medications primarily work by stimulating the release of insulin from the pancreas, which helps to lower blood sugar levels, along with other benefits like increasing fullness and decreasing hunger

This multi-receptor action sets it apart from other medications in the GLP-1 class, as it has the potential to affect a wider range of metabolic processes

Preventing severe constipation without adding gastrointestinal stress