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There are no national or international agreements of what a normal range is

Clinical research on NAD+ therapy has primarily used intravenous infusions at high doses (5001,000 mg) for applications such as addiction treatment and acute metabolic support [2] [9]

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If a person has a liver disorder, for example liver disease, then the liver is unable to store vitamin B12 and this can lead to a B12 deficiency

In a patient with normal B12 status, injecting more of it does not create surplus energy or burn fat

This represents a significant gap between regulatory approval for safety (as a food substance) and clinical efficacy (which is absent or insufficient for weight loss)