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Given the results from recent studies, the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) recommend that patients with T2D and clinical cardiovascular disease (CVD) with inadequate glucose control despite treatment with metformin should receive an SGLT2 inhibitor or GLP-1 receptor agonist

What should I do if side effects are severe

Combination care is not necessary for every patient

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Gastrointestinal symptoms

Fewer significant metabolic changes in the co-infected group ( n = 4) compared to the HIV ( n = 7) and TB ( n = 11) underscore a lack of pronounced anabolic or catabolic shifts in protein metabolism