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This study was the first to investigate some parameters in refractory epilepsy disease Data availability The datasets used and/or analyzed during the current study can be provided by the corresponding author upon reasonable request, either by providing it in a supplementary file or by depositing it in a public repository and providing the details on how to access it

In particular, ChAT expression is induced by the Th2-associated master regulator GATA3 and the suppression of RE-1 silencing transcription factor (REST)-mediated methylation of the ChAT promoter (124) ( Figure 3 )

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As for safety