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, DiMarchi, R
From there, recommendations are made clearly and practically.
In major clinical trials, tirzepatide demonstrated a higher efficacy, with patients achieving up to a 22.5% average reduction in body weight
A Weekly Schedule Grid Two dosing patterns dominate the research framing: a continuous 7-day pattern (dose every day) and a 5-on / 2-off pattern (dose Monday through Friday, rest the weekend)
This trial is designed to generate impactful data that demonstrates our ability to safely and efficiently deliver an oral GLP-1R agonist using a validated technology. Prof Carel le Roux References 1
My approach: dial back to the minimum effective dose liquid only, sipped in small amounts at every aid station
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