Research indicates that GPER expression is closely related to androgen levels, and patients with PCOS often present elevated androgen levels [157], which may lead to abnormal GPER function, thus affecting ovarian physiological functions and metabolic status [157]
doi: 10.1146/annurev-nutr-071715-050947
Yes, people with pernicious anemia need vitamin B12 for life
In advanced cases of Hashimotos and primary hypothyroidism, this lab test will be elevated
Briviba K, Fraser G, Sies H, Ketterer B (1993) Distribution of the monochlorobimane-glutathione conjugate between nucleus and cytosol in isolated hepatocytes
However, several drugs have been used "off label," including pentoxifylline (PTX) and corticosteroids