When your stomach takes more time to empty itself of food, it sends signals of fullness to the brain
These medications are contraindicated during pregnancy, and women of reproductive potential should use effective contraception during treatment
Many people switch for greater weight loss or blood sugar control
A 2026 Cochrane review found that exercise produces a moderate reduction in depressive symptoms, with effects comparable to psychological therapy
An alternative weight loss treatment is bariatric surgery
Serious shared side effects of both medications include: inflamed pancreas (very rarely) severe allergic reaction (very rarely) You should seek urgent medical help immediately if you notice: severe or prolonged stomach pain pain that moves to the back nausea and vomiting fever swelling of face, tongue, lips, or throat trouble breathing or swallowing severe rash or hives dizziness fainting All medications can potentially have side effects, and Mounjaro and Ozempic/Wegovy are no different