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Smith AJ, Kim S-H, Duggirala NK, Jin J, Wojtas L, Ehrhart J, et al

L-arginine synthesized in the liver does not reach the systemic circulation effectively because of the high activity of hepatic arginase 122,123

10.1042/BCJ20160510 144 TingN

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Autoimmune Disorders & Overactive Immune System NAD influences immune function and may activate immune cells

Juglone and other naphthoquinones are known to form adducts with glutathione even under physiological conditions, and since GSH was the substrate of ChaC1 and was in the reaction buffers at high concentrations (2 mM) this seemed very plausible