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The treatment was administered as an adjunct to a low-calorie diet for the first 8 weeks, followed by 60 weeks of intensive behavioural therapy including a hypocaloric diet and increased physical activity

Read about microdosing pharmacokinetics

Potential digestive issues, such as nausea or diarrhea, especially when consumed in high doses

Though, there is slight increase in insulin secretion over 8 weeks, paired t-test of mean change in plasma insulin at 0 week and 8 weeks is not statistically significant, with p-value = 0.7 at a 95% confidence interval

Risk depends on how warm it got and for how long - getting back to cold storage promptly is the key step

[4] [5] These effects may vary by population, dose, and baseline characteristics