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(2020) study, which contains more information not discussed here in my post Impact of supplements on live birth and pregnancy rates in women: a meta-analysis

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In further research, it was found that the neuroprotection mediated by berberine after ischemia involves the AKT/glycogen synthase kinase-3 (GSK3)/extracellular signal-regulated kinase 1/2 (ERK 1/2) signal pathway, and inhibits Jun amino-terminal kinases (JNK) and caspase-3 activity (Simes Pires et al., 2014)

However, sensitivity analyses, which involved excluding individual studies, revealed that omitting one outlier study [22], characterized by substantial variability compared to the others, resulted in a significant increase in WL for the GLP-1RAs group (SMD = 0.82

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