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The -KG produced by Gln metabolism serves as an essential substituent for type I collagen and is involved in the composition of the most abundantly expressed extracellular matrix components in fibrosis

Despite its critical importance, supplementing with standard oral glutathione has historically been highly ineffective

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Targeting GSH-deficient phenotypes with specific antioxidant interventions and studying downstream biological effects could improve our understanding of prognosis-determining factors that have a pathoplastic effect on schizophrenia

pylori colonization, enhance the effect of antibiotics and modulate the hosts immune response

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