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Recent research has identified the gut microbiota as the primary factor behind the gastrointestinal side effects of metformin (Zhang et al., 2023)

Under hyperglycemic conditions, it amplifies the insulin response without increasing the risk of hypoglycemia, a common and serious concern with many traditional antidiabetic therapies (Liu 2024

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Therefore, the investigation of TCM monomers can significantly contribute to understanding the therapeutic mechanisms of both single herbs and herbal formulations in TCM

The critical variable is whether the specific pharmacy can provide lot-level documentation particularly the benzyl alcohol assay and sterility confirmation for the product currently in distribution