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A repeated-measures two-way ANOVA revealed a significant main effect of the factors treatment (F (1,16) = 12.47, P = 0.0028), time (days) (F (5,80) = 4.437, P = 0.0012), and a significant treatment time interaction (F (5,80) = 10.89, P 0.05

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For example, a 1 mL solution with 1000 mcg/mL is the same as 1 mg/mL

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Anyone taking methyl-donor-sensitive medications (some psychiatric drugs, methotrexate, methylated B-vitamin protocols at high doses): NNMT shares the methyl donor SAM, so theoretical interactions exist

Combine low intake with impaired absorption, and deficiency becomes highly probable without supplementation