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Nonetheless, during methicillin-resistant Staphylococcus aureus (MRSA) skin infection, rescuing PGE 2 effects in diabetic mice, using a topical treatment with misoprostol, rescued DC migration to draining lymph nodes, Th17 differentiation, and improved host defense [51] suggesting that PGE 2 effects during efferocytosis of infected cells are context-dependent

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Toxicol Appl Pharmacol 187, 110