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It has been shown to produce significant weight loss when combined with healthy eating and exercise

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Gastrointestinal Disease Since cobalaminIF complex receptors are located in the ileum, chronic gastrointestinal disease, alimentary lymphoma, and ileum resection can lead to cobalamin deficiency, as these conditions reduce ileum absorption capacity [35]

For injectable routes, such as subcutaneous, research models might start with doses around 0.5mg to 2mg daily for an equivalent 70kg subject