In pooled data from nine clinical trials, canagliflozin was associated with bone fractures (1.4, 1.5, and 1.1/100 patient-years for canagliflozin 100, 300 mg, and comparators, respectively) [45]
While the full implications are still being studied, this is a conversation every endometriosis patient of reproductive age should have with their fertility specialist before starting a GLP-1 medication
It is not recommended to take it early (even by a day) or late
PMC 4446791
This first-of-its-kind drug launch helped meet the incredible demand for the only FDA-approved oral GLP-1 weight loss medication and make it one of the most successful launches ever
It is, therefore, important to provide primary care clinicians with the clinical evidence as well as a simple and pragmatic tool that could aid the decision-making process