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In cardiovascular disease, emerging cardiac MRI techniques, including T1 mapping and extracellular volume fraction, offer quantitative assessment of myocardial fibrosis, while circulating collagen turnover markers may provide complementary information

A general guideline is to exhale during the most challenging part of the movement (e.g., pushing the weight up in a press, standing up from a squat) and inhale during the easier phase

Gastrointestinal symptoms - Diarrhea, constipation, abdominal discomfort, vomiting Reduced appetite - While this contributes to weight loss, some people find it makes eating adequate nutrition challenging Fatigue - Some individuals report feeling more tired, particularly in the first few weeks Injection site reactions - Redness, itching, or mild discomfort at injection sites (for injectable formulations) Most side effects are dose-dependent and tend to improve as the body adjusts

Multi-dose pens (after first use): Ozempic (semaglutide): May be stored at room temperature (up to 86F/30C) for up to 56 days or kept refrigerated after first use [1] [2] Victoza and Saxenda (liraglutide): May be kept at room temperature (up to 86F/30C) for up to 30 days or refrigerated after first use Byetta (exenatide): May be kept at room temperature (up to 77F/25C) for up to 30 days after first use Single-dose pens (before use): Wegovy (semaglutide): May be stored at room temperature (up to 86F/30C) for up to 28 days before use [1] [2] Trulicity (dulaglutide): May be stored at room temperature (up to 86F/30C) for up to 14 days before use Mounjaro and Zepbound (tirzepatide): May be stored at room temperature (up to 86F/30C) for up to 21 days before use Bydureon BCise (exenatide extended-release): May be stored at room temperature (up to 77F/25C) for up to 4 weeks before use Patients should write the date of first use on multi-dose pen labels to track how long the medication has been in use