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Erianin induces specific cell death modalities such as ferroptosis via the JAK/STAT pathway and reverses chemotherapy resistance (21) and reprograms metabolism through the Wnt/-catenin pathway (16)

This effect can result in aspiration as the bodys natural gag response is suppressed by CNS depression

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For example, PARP1 binds a DNA single strand break, then utilizes NAD + to ADP-ribosylate macromolecules in the vicinity, a signal for recruitment of DNA repair machinery 6

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