Phase 1 multicenter dose-escalation study of ezatiostat hydrochloride (TLK199 tablets), a novel glutathione analog prodrug, in patients with myelodysplastic syndrome
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TRPV1 is a homotetrameric membrane protein belonging to the transient receptor potential channel (TRP) family of which there are six known channels
Another potential mechanism could be the role of NAD + consuming PARP enzymes which are involved in repairing DNA damage, which could be induced by chemotherapy
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Elevated serum BAFF levels are associated with rising antidoublestranded DNA antibody levels and disease flare following B cell depletion therapy in systemic lupus erythematosus