J Neurosci (2012) 32(40):137018
Dopamine-supportive therapy Targets reward pathway reactivation
One 2024 study at the Smell and Taste Center at the University of Pennsylvania (source) found evidence of GLP1 agonists significantly depressing the perception of all five basic taste qualities. Interestingly, while all participants in the study experienced a slight decline in their sense of smell, it was not considered statistically significant suggesting that olfactory changes may be more individualised, or more complex to detect in standardised tests
Available in 3 mg, 7 mg, and 14 mg tablets, Rybelsus is a reasonable option if the logistics of transporting injectable medication concern you
More recent research continues to suggest that there may be a signal worth paying attention to
GLP-1RA Mechanism of Action GLP-1 (glucagon-like peptide-1) is a hormone secreted by the intestinal tract during feeding, which enhances insulin secretion and inhibits glucagon secretion in a glucose concentration-dependent manner, and delays gastric emptying to reduce the amount of food eaten through central appetite suppression
