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Effects of DPP-4 inhibitor linagliptin and GLP-1 receptor agonist liraglutide on physiological response to hypoglycaemia in Japanese subjects with type 2 diabetes: a randomized, open-label, 2-arm parallel comparative, exploratory trial

Although the GIP and GIP receptor system is known to promote energy assimilation and contribute to obesity [26], the fact that a dual GIP/GLP-1R agonist exhibited stronger anti-obesity effects than GLP-1RAs alone was unexpected