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and broad transcriptional effects, with gene-expression analyses identifying modulation of expression patterns associated with antioxidant defense, DNA repair, and tissue remodeling

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It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element

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While measurement of LPS in healthy individuals is difficult due to its low levels and issues with contaminated lab equipment, inhibition of LPS-receptor, the toll-like receptor 4 (TLR4), reduces blood pressure (BP) and inflammatory markers (e.g., IL6, macrophage infiltration to the kidneys) in experimental models of hypertension [17, 18]