glp-1 and neuroinflammation Repurposing glucagon-like peptide-1 receptor agonists for the treatment of neurodegenerative disorders Glucagon-like peptide-1 suppresses neuroinflammation and

GLP-1R expression is found in macrophages and fibroblast-like synoviocytes, which are important for maintaining synovial fluid homeostasis

GLP-1 wars The biggest pharma trade of the decade is breaking in real time

Which is a shame, because underneath the marketing there's a genuinely reasonable clinical idea, one that happens to matter more for midlife women than for almost anyone else

Even though GLP-1s were initially studied for their role in insulin secretion regulations, we now know that they have actions across different organs, and they are also widely expressed in the brain, raising the possibility that they may have direct [central nervous system] effects, Afsaneh Shirani, MD, board certified neurologist at Saint Luke's Marion Bloch Neuroscience Institute and the University of Missouri-Kansas City, told attendees

Its taken by mouth

doi: 10.1111/dom.12932, 9 BoothM