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Pain levels are generally described as mild

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Effective beginner concentrations are 1 to 2%

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Heinzerling L, Ascierto PA, and Dummer R, et al (2019) Adverse events 2.0-Let us get SERIOs: new reporting for adverse event outcomes needed in the era of immunooncology Eur J Cancer 112 2931 PMID: 30903870 77