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Importantly, RH-F/C-NPs markedly upregulated barrier-associated proteins including occludin, claudin-1, and ZO-1, underscoring their therapeutic potential for epithelial injury repair (194197)

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4-HNE represents a highly reactive lipid peroxidation byproduct that induces cellular damage by interacting with proteins, DNA, and other cellular components through iron- and oxygen-mediated chain-breaking reactions (7)

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