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Epitalon is a precisely defined synthetic tetrapeptide with the amino acid sequence Ala-Glu-Asp-Gly

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And perhaps most importantly, the rate of treatment discontinuation, which reveals how tolerable each treatment is in the real world rather than in the controlled environment of separate trials

Quick Reference: Common Concentrations IU = insulin units on a U-100 syringe (100 IU = 1mL)

The reasons cited by the FDA included concerns about immunogenicity, peptide impurity characterization challenges, and the lack of adequate safety data from human clinical trials