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After reaching the target dose, the 2.4 mg/week dose was sustained for an additional 16 weeks

It should not be described as the complete pineal extract or as a pineal hormone

Rong H, et al

Much of the current evidence is preclinical (cell and animal studies), and human data is still limited

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In rodent and rabbit models of hypoxia and myocardial I/R, LONP1 shows a time-dependent upregulation at both the transcriptional and translational levels