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Conclusion: Altogether, our results show that the cellular antioxidant defense systems contribute to leukemia resistance to MTX, and targeting these pathways, especially the thioredoxin antioxidant system, may be a promising strategy for resensitizing ALL to MTX

AOD 9604 isnt appropriate for everyone, such as those who: Before starting, inform your prescriber if youre taking the following medication to prevent harmful drug interactions: Your licensed clinician should run baseline laboratory tests before starting your dosing, which they must always supervise

2021;1862(1):148317.[DOI] 40

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