What they found: In normal obese mice: AOD-9604 reduced body fat by 21 % vs placebo, hGH by 24 % The AOD-9604 effect was fully dependent on the 3-adrenergic receptor , in knock-out mice no effect The hGH effect was partly independent of 3-AR , in knock-out mice there was still ~10 % fat reduction AOD-9604 did not raise IGF-1 (control level), whereas hGH raised IGF-1 by 80 % No changes in growth, organ weights (except adipose tissue), fasting insulin Why it matters: The study provided the mechanistic basis for AOD-9604 and confirmed the key business hypothesis: it is possible to separate the lipolytic effect of GH from its growth effect
The B12 I get come in 10,000 mcg vials
Creatine supplementation Creatine is one of the most researched and effective supplements for muscle preservation and performance
All the information I shared in this blog provided education about Vit B12 & skin issues
Research demonstrates that collagen peptides working through TGF-/Smad3 pathway activation can reduce MMP-3, MMP-13, MMP-2, and MMP-9 activity while increasing procollagen synthesis, attenuating the collagen degradation characteristic of photoaged skin
How AOD-9604 Works at the Molecular Level AOD-9604 mimics the lipolytic (fat-burning) region of human growth hormone without binding to growth hormone receptors
