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People included in the trial were aged 45 years with a BMI 27 kg/m2

The selection and use of essential medicines, 2025: WHO Model List of Essential Medicines, 24th list

Semaglutide GLP-1 is now recommended by the FDA for chronic weight management in patients with a BMI greater than 30 kg/m2 or 27 kg/m2 but having at least one obesity-related comorbidity

Approval (2017) FDA news release (March 8th, 2024): FDA Approves First Treatment to Reduce Risk of Serious Heart Problems Specifically in Adults with Obesity or Overweight Weight Regain And Cardiometabolic Effects After Withdrawal Of Semaglutide: The Step 1 Trial Extension (May 19, 2022) US CDC: Adult Activity: An Overview (Dec 20, 2023)

More participants in the semaglutide group than in the placebo group achieved weight reductions of 5% or more (1047 participants [86.4%] vs

Al adelgazar, la demanda de insulina basal, la dictada por la necesidad de 1 UI por kg y da, disminuye