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In the first study, which lasted 28 days, CJC-1295 or placebo was administered in one of four ascending single doses

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ME wrote the article, XG wrote and critically reviewed the article and EI wrote and critically reviewed the article

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found that system Xc expression in microglia affects their M1/M2 status: loss of system Xc reduces glutamate release, shifts microglia toward the M2 phenotype, and enhances motor neuron survival (373)