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Mangiferin directly binds to Keap1, activates the downstream Nrf2/SLC7A11/GPX4 pathway, inhibits osteoblast ferroptosis, promotes bone formation and improves osteoporosis in ovariectomized mice and iron overload mice

The Journal of clinical investigation 112 , 608618, doi: 10.1172/JCI17305 (2003)

Newer trials may have different durations

This increases the risk of developing kidney stones

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Con frecuencia, los profesionales de la salud tienen acceso a estudios recientes y datos clnicos fiables que revelan incluso aspectos menos conocidos, como los efectos a largo plazo o las contraindicaciones especficas