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In this setting, metabolic durability may depend on maintaining cofactor availability within physiological ranges rather than pursuing aggressive replacement strategies

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Therefore, the ratio of GSH and GSSG has been focused as an index of oxidative stress

(2016) studied the association of TMAO with acute HF and found that circulating TMAO is an independent biomarker for predicting mortality and death/re-hospitalization due to HF within 1 year when renal function was excluded

This physiological response activates heat-induced adaptations similar to those produced by moderate-intensity exercise

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