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Description

Effectiveness of semaglutide and tirzepatide in overweight and obese adults with type 1 diabetes

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GLP-1 (glucagon-like peptide-1) is a naturally occurring hormone produced in the intestines after eating

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Sitagliptin, a dipeptidyl peptidase-4 inhibitor, was selected as an active-comparator placebo proxy because it was recommended in clinical guidelines as a second-line glucose-lowering therapy, had a similar high cost to the study drugs, showed no effect on cardiovascular outcomes in a large randomized controlled trial and has been validated as a placebo proxy in prior claims-based research 20,41

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J Neurosci Res 2007

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Food and Drug Administration (FDA), has fostered an estimated $2.2 billion underground market

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