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use is only in addition to lifestyle modifications, according to the guideline

Tenofovir-disoproxil-fumarate modulates lipid metabolism via hepatic CD36/PPAR-alpha activation in Hepatitis B virus infection

a prospective randomized single-blind clinical trial

Finally, in patients not receiving sedatives, no significant differences in ISI change were observed between treatment types or response status

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The sample depletion of the target compound was less than 5%, i.e., the criterion of negligible depletion 28